|24 March 1927||Tambo,Australia||de Havilland DH.9C||G-AUED||Stalled at low altitude on approach to land.||3||3|
|4 September 1928||Adelaide Hills,Australia||de Havilland.50J||G-AUHI||Following a tour carrying Sir John Salmond, aircraft departed Adelaide piloted by C.W.A. Scott with engineer as passenger; lost control in cloud during attempt to cross the Adelaide Hills and aircraft crashed and caught fire killing the engineer.||2||1|
|3 October 1934||Near Winton,Australia||de Havilland.50A||VH-UHE||Crashed after in-flight loss of control, possibly stalled at low altitude in dusty low-visibility conditions.||3||3|
|15 November 1934||Near Longbeach,Australia||de Havilland.DH86||VH-USG||Crashed on its delivery flight from England to Brisbane after in-flight loss of control, probably due to the type's design deficiencies.||4||4|
|30 January 1942||Timor Sea off Kupang||Shorts S.23 Empire Flying Boat||G-AEUH||Shot down by Japanese aircraft; ex-Qantas VH-ABD, owned by Imperial Airways and operated by Qantas.||18||13|
|20 February 1942||Brisbane,Australia||de Havilland.DH86||VH-USE||Lost control after take-off in stormy weather, possibly broke-up in flight (tail fin found a mile from the crash site).||9||9|
|28 February 1942||Tjilatjah, Netherlands East Indies||Shorts S.23 Empire Flying Boat||G-AETZ||Shot down by Japanese aircraft; ex-Qantas owned by Imperial Airways and operated by Qantas.||20||20|
|22 April 1943||Gulf of Papua off Port Moresby,Papua||Shorts S.23 Empire Flying Boat||VH-ADU||Broke up in heavy seas after emergency landing in open water in poor weather.||31||13|
|26 November 1943||Port Moresby,Papua||lockheed C-56B lodestar||42-68348||Struck hill after take-off; USAAF aircraft operated by Qantas for Allied Directorate of Air Transport.||15||15|
|11 October 1944||Rose Bay,Sydney Australia||Shorts S.23 Empire Flying Boat||VH-ABB||On final approach with one engine shut-down, stalled 3 metres (10 ft) above the water and hull ruptured on impact.||30||1|
|23 March 1946||Indian Ocean||Avro Lancastrian||G-AGLX||Aircraft disappeared between Colombo and the Cocos (keeling) islands,cause unknown; aircraft owned by BOAC and operated by both airlines on Sydney-London services (BOAC crews operated London-Karachi and Qantas crews Karachi-Sydney).||10||10|
|16 July 1951||Huon Gulf near Lae,Papua New Guinea||de Havilland Australia DHA-3 Drover||VH-EBQ||Crashed in sea after centre propeller failure.||7||7|
- On 24 August 1960,plane:Lockheed L1049 Super Constellation.During takeoff from runway 13, engine number 3 lost power just before reaching the V1 speed of 115 knots. The captain pulled off the power, braked hard, and pulled selected reverse thrust. The aircraft however, did not decelerate as expected. The flight engineer feathered the number 3 engine and pulled its emergency shut-off valve. The Super Constellation, named "Southern Wave", could not be brought to a stop on the remaining runway and overran the runway at a speed of 40 knots. The airplane bounced over a low embankment, crashed into a gulley and caught fire.
- On 23 September 1999, Qantas Flight 1:a Boeing 747–400 VH-OJH, overran the runway while landing at Bangkok,Thailand during a heavy thunderstorm. The aircraft ended up on a golf course, but without fatalities. The Australian Transport Safety Bureau criticised numerous inadequacies in Qantas' operational and training processes.
- On 25 July 2008, Qantas Flight 30 a Boeing 747–400 VH-OJK, on the leg from Hong kong to Melbourne, suffered a rapid decompression and made an emergency landing in Manila after an explosion. There were no injuries. The ATSB officially stated that the incident was caused by the failure of an oxygen tank.
- On 7 October 2008, Qantas Flight 72:an Airbus A330-300 VH-QPA "Kununurra" travelling from Singapore to Perth suffered a rapid loss of altitude in two sudden uncommanded pitch down manoeuvres causing serious injuries while 80 nautical miles (150 km) from Learmonth, Australia. The aircraft safely landed in Learmonth, with 14 people requiring transportation by air ambulance to Perth. Another 30 people also required hospital treatment, while an additional 30 people had injuries not requiring hospital treatment.Initial investigations identified an inertial reference system fault in the Number-1 Air Data Inertial Reference Unit as the likely origin of the event. On receiving false indication of a very high angle of attack, the flight control systems commanded a pitch down movement, reaching a maximum of 8.5 degrees pitch down.
- On 4 November 2010 Qantas Flight 32: an Airbus A380, named "Nancy-Bird Walton" and registered VH-OQA, fitted with four Trent 972 engines manufactured by Rolls-Royce suffered an uncontained turbine disc failure of its left inboard engine shortly after taking off from Singapore Changi Airport.The flight returned to Singapore and landed safely, and all 433 passengers and 26 crew on board survived uninjured. Cowling parts of the failed engine fell over Batam island,Indonesia.